Description

Carbamoylphosphate: L-Ornithine Carbamoyltransferase is a critical enzyme that catalyzes the transfer of a carbamoyl group from carbamoyl phosphate to L-ornithine, forming L-citrulline. This reaction is a fundamental step in the urea cycle, making the enzyme essential for research into nitrogen metabolism, liver function, and related metabolic disorders. It is primarily utilized by biochemical researchers, diagnostic kit manufacturers, and pharmaceutical developers requiring high-purity, reliable enzymatic activity for their assays and development processes.

Application

• Biochemical Research: Essential reagent for in vitro studies of the urea cycle, nitrogen metabolism, and hepatic function.
• Diagnostic Manufacturing: Key component in the production of clinical diagnostic kits for measuring ornithine transcarbamylase (OTC) activity and diagnosing related deficiencies.
• Enzyme Kinetics Studies: Used to investigate reaction mechanisms, inhibition, and catalytic efficiency of transcarbamylase enzymes.
• Pharmaceutical Development: Employed in screening and research for potential therapeutics targeting urea cycle disorders.
• Educational & Reference Standards: Serves as a purified enzyme standard for academic teaching and quality control in laboratory settings.

Basic Information

Product Name	Carbamoylphosphate: L-Ornithine Carbamoyltransferase
CAS No.	9001-69-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ornithine Transcarbamylase; OTCase; Ornithine Carbamoyltransferase; Carbamoyl Phosphate: L-Ornithine Carbamoyltransferase; OTC; EC 2.1.3.3; L-Ornithine Carbamoyltransferase; Ornithine Transcarbamylase (OTC)
EINECS	Contact for details

Quality Control

Our Carbamoylphosphate: L-Ornithine Carbamoyltransferase is produced and tested under stringent quality management systems. Each lot undergoes rigorous analytical testing to ensure high specific activity, purity, and stability. A comprehensive Certificate of Analysis (COA) detailing assay results, purity, and activity is provided with every shipment to guarantee consistency and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which can affect enzymatic activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Identification (Activity)	Conforms (Specific activity provided on COA)
Protein Content (Biuret)	>90%
Specific Activity	≥ 20 units/mg protein
Purity (SDS-PAGE)	Single major band
Solubility	Clear, colorless solution in recommended buffer
pH (in solution)	7.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.