Description

Ec 1.1.1.67 CAS NO 9001-65-4 is a high-purity enzyme preparation, specifically identified as Mannitol 2-dehydrogenase (NAD+). This biocatalyst is essential for the stereospecific oxidation of mannitol to fructose, a critical reaction in carbohydrate metabolism and industrial bioprocesses. It is a vital reagent for biochemical research, diagnostic kit manufacturing, and the development of enzymatic synthesis pathways in the pharmaceutical and fine chemical industries.

Application

• Biochemical Research & Assay Development: Used as a key enzyme in metabolic pathway studies, enzyme kinetics research, and the development of analytical methods for carbohydrate analysis.
• Diagnostic Manufacturing: Serves as a critical component in the formulation of clinical diagnostic kits for measuring mannitol, fructose, or related metabolites in biological samples.
• Enzymatic Synthesis: Employed in the biocatalytic production of rare sugars and sugar alcohols, offering a green and selective alternative to traditional chemical synthesis.
• Pharmaceutical Intermediates: Facilitates the synthesis of chiral intermediates for pharmaceutical active ingredients where high stereoselectivity is required.
• Food & Beverage Analysis: Applied in quality control laboratories for the enzymatic determination of sugar profiles in food products and beverages.
• Academic & Teaching Laboratories: Supplied to universities and research institutions for educational purposes in biochemistry and enzymology courses.

Basic Information

Product Name	Ec 1.1.1.67 CAS NO 9001-65-4
CAS No.	9001-65-4
Molecular Formula	N/A (Enzyme)
Molecular Weight	Varies by preparation (Contact for details)
Synonyms	Mannitol 2-dehydrogenase; NAD+-dependent mannitol dehydrogenase; MDH; EC 1.1.1.67; D-Mannitol dehydrogenase; Polyol dehydrogenase; 1.1.1.67; Mannitol dehydrogenase (NAD+); D-Mannitol:NAD+ 2-oxidoreductase
EINECS	232-625-8

Quality Control

Our Ec 1.1.1.67 enzyme is produced and tested under stringent quality management systems. Each lot is characterized for specific activity, purity, and stability to ensure reproducible performance in your applications. We provide comprehensive Certificates of Analysis (COA) detailing activity units, protein content, and impurity profiles. Our quality commitment aligns with the standards expected for research and diagnostic-grade enzymes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ [Value] units/mg protein
Protein Content (Biuret)	≥ [Value] %
Purity (SDS-PAGE)	≥ [Value] %
pH Optimum	~9.0 - 10.5
Temperature Optimum	~25 - 37°C
Stabilizers	May contain glycerol or buffer salts
Activity Loss (at -20°C)	< 5% per year

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.