Description

Hyaluronidase is a hydrolytic enzyme that catalyzes the breakdown of hyaluronic acid, a key component of the extracellular matrix. This action is critical for enhancing the dispersion and absorption of other injected substances, making it a vital pharmaceutical adjunct. It is primarily utilized in the pharmaceutical, biotechnology, and research sectors for applications ranging from drug delivery to tissue preparation. Hyaluronidase CAS NO 9001-54-1 is available in various grades to meet specific industry requirements.

Application

• Pharmaceutical Adjuvant: Used to increase the absorption and dispersion of other drugs (e.g., local anesthetics, antibiotics, contrast media) administered via subcutaneous or intramuscular injection.
• Ophthalmic Surgery: Facilitates the spread of local anesthetics and helps in the management of vitreous hemorrhage.
• Dermatology & Aesthetics: Employed as an antidote to correct complications from hyaluronic acid-based dermal fillers by rapidly dissolving the filler material.
• Diagnostic Procedures: Enhances the diffusion of subcutaneously administered diagnostic agents for improved imaging.
• Research & Biotechnology: A key reagent for tissue dissociation, cell isolation, and studying the role of hyaluronic acid in cell biology, cancer research, and wound healing.
• Improving Subcutaneous Fluid Administration: Used in hypodermoclysis to facilitate the absorption of large volumes of fluids.

Basic Information

Product Name	Hyaluronidase
CAS No.	9001-54-1
Molecular Formula	N/A (Enzyme)
Molecular Weight	~61,000 Da (Approximate, varies by source)
Synonyms	Hyaluronoglucosaminidase; Hyaluronate Lyase; Spreading Factor; Hyalase; Wydase; Alidase; Hyazyme; Hyaluronidase from bovine testes; Hyaluronidase BP; Hyaluronidase USP
EINECS	232-645-9

Quality Control

Our Hyaluronidase is produced and tested under strict quality management systems. Each batch is characterized for critical parameters including enzymatic activity (USP/BP units), protein content, and purity to ensure consistent performance and reliability in your formulations. Certificates of Analysis (COA) detailing specific results for identity, assay, and microbiological quality are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White or off-white powder or lyophilized solid
Identification (IR)	Conforms to standard
Activity (USP/BP Units)	As per label claim
Protein Content (Biuret)	≥ 95%
pH (in solution)	6.0 - 7.5
Loss on Drying	≤ 5.0%
Microbial Limits	Meets Ph. Eur./USP requirements
Endotoxin (LAL)	< 1.0 EU/Unit (for injectable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.