Description

Ec 1.6.4.2 CAS NO 9001-48-3 is a high-purity enzyme preparation, specifically identified as Glutathione Reductase (GR). This critical biocatalyst plays an essential role in maintaining cellular redox balance by catalyzing the reduction of oxidized glutathione. It is indispensable for research and development in life sciences, diagnostics, and pharmaceutical manufacturing, where precise enzymatic activity is required. Key industries that rely on this product include biotechnology, academic research, and diagnostic kit production.

Application

• Biochemical Research & Assay Development: Used as a key component in enzymatic assays to study oxidative stress, antioxidant mechanisms, and redox signaling pathways.
• Diagnostic Kit Manufacturing: Serves as a critical reagent in clinical diagnostic kits for measuring glutathione levels, which are indicators of various health conditions.
• Pharmaceutical Development: Employed in drug discovery and screening processes targeting diseases related to oxidative damage, such as neurodegenerative disorders.
• Cell Culture & Biotechnology: Utilized in bioprocessing to help maintain the health of cell lines by mitigating reactive oxygen species (ROS) in culture media.
• Food & Nutraceutical Analysis: Applied in quality control laboratories to assay antioxidant capacity and stability in food products and dietary supplements.
• Environmental Toxicology Studies: Used as a biomarker in ecotoxicology to assess the impact of pollutants on the antioxidant defense systems of organisms.

Basic Information

Product Name	Ec 1.6.4.2 (Glutathione Reductase)
CAS No.	9001-48-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Glutathione Reductase (GR); NADPH-Glutathione Reductase; Glutathione-Disulfide Reductase; GSR; GRase; EC 1.6.4.2; Glutathione Reductase (NADPH); Glutathione:NADP+ Oxidoreductase
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized for specific activity, purity, and stability to meet the stringent requirements of research and industrial applications. Certificates of Analysis (COA) detailing parameters such as activity units/mg protein, purity by SDS-PAGE, and absence of contaminating activities are available upon request. We adhere to relevant quality management principles to ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). For short-term use, aliquots may be stored at 2-8°C. Avoid repeated freeze-thaw cycles to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported on COA
pH (in solution)	7.0 - 7.5
Stability	Retains ≥ 90% activity after 12 months at -20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.