Description

Human Fibrinogen is a critical plasma glycoprotein essential for the final stage of the blood coagulation cascade, forming the structural matrix of a blood clot. Its high purity and biological activity make it indispensable for advanced research and therapeutic applications. This product is primarily utilized by the biopharmaceutical, diagnostic, and biomedical research industries for developing hemostatic agents, tissue engineering scaffolds, and in vitro diagnostic assays.

Application

• Hemostatic Agent Formulation: Key component in fibrin sealants and glues used in surgical procedures to control bleeding and promote wound healing.
• Biomedical Research: Used in coagulation studies, cell culture substrates, and investigating thrombosis and hemostasis mechanisms.
• Tissue Engineering: Serves as a biodegradable scaffold material for regenerative medicine, supporting cell growth and tissue repair.
• Diagnostic Manufacturing: Essential raw material in the production of calibrators, controls, and reagents for coagulation testing kits (e.g., PT, APTT).
• Pharmaceutical Development: Employed in the R&D of novel drug delivery systems and biotherapeutics targeting the coagulation pathway.

Basic Information

Product Name	Human Fibrinogen
CAS No.	9001-32-5
Molecular Formula	Contact for details
Molecular Weight	~340 kDa (Complex)
Synonyms	Factor I; Fibrinogen, Human; Plasma Fibrinogen; Coagulation Factor I; Fibrinogen Concentrate; Fibrinogen Human; Fibrinogen (Human); Fibrinogen Aα, Bβ, γ chain complex
EINECS	232-614-6

Quality Control

Our Human Fibrinogen is manufactured and tested under stringent quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting high standards for research and pharmaceutical applications. Certificates of Analysis (COA) detailing specifications such as clottable protein content, solubility, and biological activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive (protect from all light exposure). For long-term storage, keep desiccated. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms
Clottable Protein	> 90% (by weight)
Solubility	Clear, slightly opalescent solution in specified buffer
Moisture (Loss on Drying)	< 5.0%
pH (in solution)	6.5 - 7.5
Biological Activity (Clotting)	Meets release criteria
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.