Description

Human Factor Ix is a highly purified plasma-derived glycoprotein, also known as Coagulation Factor IX, which is essential for the blood coagulation cascade. This product is critical for ensuring reliable and consistent performance in therapeutic and diagnostic applications where precise biological activity is required. It is primarily utilized by biopharmaceutical manufacturers, clinical diagnostic laboratories, and research institutions developing treatments for coagulation disorders such as Hemophilia B.

Application

• Therapeutic Formulations: As the active pharmaceutical ingredient (API) in replacement therapy for patients with Hemophilia B (Christmas disease).
• Diagnostic Reagents: A key component in coagulation factor assay kits and control plasmas for clinical laboratory testing.
• Biomedical Research: Used in studies of the intrinsic coagulation pathway, protein-protein interactions, and hemostasis mechanisms.
• Biopharmaceutical Development: Serves as a reference standard in the quality control and potency testing of Factor IX products.
• Cell Culture & Biochemistry: Employed in specialized cell culture media and biochemical studies requiring defined coagulation factors.

Basic Information

Product Name	Human Factor Ix
CAS No.	9001-28-9
Molecular Formula	Contact for details
Molecular Weight	Approx. 55,000 Da (Monomer)
Synonyms	Coagulation Factor IX; Christmas Factor; Plasma Thromboplastin Component (PTC); Antihemophilic Factor B; FIX; Factor 9; Blood Coagulation Factor IX; EC 3.4.21.22; F9 Protein; Human Coagulation Factor IX
EINECS	Contact for details

Quality Control

Our Human Factor Ix is manufactured and tested under strict quality systems. Each batch undergoes comprehensive analysis to ensure identity, purity, potency, and safety, adhering to relevant pharmacopoeial guidelines. A detailed Certificate of Analysis (COA), providing specifications for assay, specific activity, purity by SDS-PAGE, and absence of key contaminants, is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. For long-term storage, consider aliquoting and storing at -20°C or below under desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (IR / Electrophoresis)	Conforms to standard
Assay (Clotting / Chromogenic)	> 95% of labeled activity
Specific Activity	≥ 200 IU/mg protein
Purity (SDS-PAGE)	> 95% (Single band)
pH (Reconstituted Solution)	6.5 - 7.5
Moisture (Karl Fischer)	< 3.0 %
Endotoxin (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.