Description

Hemocoagulase is a potent enzyme complex derived from snake venom, primarily from *Bothrops atrox*, with the CAS registry number 9001-13-2. It functions as a critical hemostatic agent by converting prothrombin to thrombin, thereby accelerating the blood clotting cascade. This product is essential for manufacturers in the pharmaceutical and biotechnology sectors requiring a reliable, high-purity active ingredient for hemostatic preparations, surgical aids, and diagnostic reagents.

Application

• Pharmaceutical Hemostats: Primary active ingredient in topical and injectable formulations to control capillary bleeding during surgical procedures.
• Surgical Adhesives & Sealants: Used as a key component in fibrin sealants and tissue adhesives to promote rapid wound closure and healing.
• Diagnostic Reagents: Employed in clinical laboratory kits for coagulation tests, such as prothrombin time (PT) and activated partial thromboplastin time (aPTT) assays.
• Research & Development: Vital biochemical tool for studying blood coagulation mechanisms, enzyme kinetics, and developing new therapeutic agents.
• Veterinary Medicine: Incorporated into hemostatic products for controlling bleeding in veterinary surgeries and trauma care.

Basic Information

Product Name	Hemocoagulase
CAS No.	9001-13-2
Molecular Formula	Protein (Enzyme Complex)
Molecular Weight	Approx. 30-40 kDa (Contact for details)
Synonyms	Bothrops atrox Venom Coagulant; Batroxobin; Reptilase; Defibrase; Botropase; Coagulating Enzyme; Thrombin-like Enzyme; Venzyme
EINECS	Contact for details

Quality Control

Our Hemocoagulase is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, potency, and safety, meeting the stringent requirements for pharmaceutical-grade active ingredients. Certificates of Analysis (COA) detailing specific tests for activity (IU/mg), protein content, and purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to Standard
Assay (Clotting Activity)	≥ 1000 IU/mg
Protein Content (Biuret)	≥ 90%
pH (1% Solution)	6.5 - 7.5
Loss on Drying	≤ 5.0 %
Bacterial Endotoxins	< 10 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.