Description

Kallikrein CAS NO 9001-01-8 is a proteolytic enzyme belonging to the serine protease family, known for its ability to cleave kininogen to release vasoactive kinins. This biochemical activity makes it a critical reagent in pharmaceutical research, diagnostic development, and biochemical studies. It is essential for researchers and manufacturers in the biopharmaceutical, diagnostic, and life science sectors who require high-purity enzymes for kinin system analysis, drug discovery, and clinical assay development.

Application

• Pharmaceutical Research & Drug Discovery: Used as a key enzyme in studying the kinin-kallikrein system, inflammation pathways, and for screening potential enzyme inhibitors.
• Diagnostic Reagent Manufacturing: Employed in the production of clinical diagnostic kits for measuring kininogen, prekallikrein, and other related biomarkers.
• Biochemical & Physiological Studies: Serves as a standard or reagent in laboratory research to investigate blood pressure regulation, pain response, and vascular permeability.
• Enzyme Characterization & Proteomics: Utilized in enzymatic assays and proteomic research to understand substrate specificity and protease activity.
• Reference Standard: Acts as a purified reference material for quality control and calibration in analytical laboratories.

Basic Information

Item	Detail
Product Name	Kallikrein
CAS No.	9001-01-8
Molecular Formula	N/A (Protein)
Molecular Weight	Approx. 25-45 kDa (Isoform dependent)
Synonyms	Kininogenin; Pancreatic Kallikrein; Tissue Kallikrein; Glandular Kallikrein; Kallikrein 1; KLK1; Kinin-Forming Enzyme; Kininogenase; EC 3.4.21.35
EINECS	232-588-9

Quality Control

Our Kallikrein is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure high purity, specific activity, and consistency. Specifications typically align with research-grade and diagnostic reagent standards. A detailed Certificate of Analysis (COA) documenting purity (by SDS-PAGE/HPLC), specific activity (by chromogenic substrate assay), and absence of contaminating proteases is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). For short-term use, aliquots may be stored at 2-8°C. Avoid repeated freeze-thaw cycles to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR / Activity)	Conforms
Protein Content (Biuret)	≥ 90%
Specific Activity	Contact for details
Purity (SDS-PAGE)	≥ 95%
Loss on Drying	≤ 5.0%
Endotoxin (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.