Description

Chloramphenicol Sodium Succinate is the water-soluble sodium salt of the succinate ester of chloramphenicol, a broad-spectrum bacteriostatic antibiotic. This formulation is critical for enabling parenteral administration, providing a vital therapeutic option where oral or topical routes are not feasible. It is primarily required by pharmaceutical manufacturers and compounding facilities for the production of injectable solutions used in human and veterinary medicine to treat serious systemic infections.

Application

• Injectable Antibiotic Formulations: Primary use in the manufacture of sterile injectable solutions for intravenous or intramuscular administration.
• Hospital & Critical Care Medicine: Used in treating severe infections like typhoid fever, meningitis, and rickettsial diseases where other antibiotics are ineffective or contraindicated.
• Veterinary Pharmaceuticals: Incorporated into injectable products for treating bacterial infections in livestock and companion animals.
• Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) in microbiological and pharmacological research.
• Compounding Pharmacy: Used by specialized pharmacies to prepare patient-specific parenteral medications.

Basic Information

Item	Detail
Product Name	Chloramphenicol Sodium Succinate
CAS No.	982-57-0
Molecular Formula	C15H15Cl2N2NaO8
Molecular Weight	445.18 g/mol
Synonyms	Chloramphenicol Succinate Sodium Salt; Chloramphenicol Sodium Succinate; Sodium Chloramphenicol Succinate; Chloramsaar; Chloromycetin Succinate Sodium; D-(-)-Three-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide α-(Sodium Succinate); CLS; Levomycetin Sodium Succinate
EINECS	213-567-6

Quality Control

Our Chloramphenicol Sodium Succinate is manufactured and tested under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with testing typically including identification, assay, impurity profile, and specific tests for related substances. A comprehensive Certificate of Analysis (COA) documenting purity, potency, and compliance is supplied with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to yellowish-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	6.0 - 7.5
Water (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Chloramphenicol	≤ 1.0%
Bacterial Endotoxins	< 0.2 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.