Description

Thiamphenicol CAS NO 2393-92-2 is a synthetic broad-spectrum antibiotic belonging to the amphenicol class, structurally related to chloramphenicol. It is valued for its potent bacteriostatic activity against a wide range of Gram-positive and Gram-negative bacteria. This compound is essential for the pharmaceutical industry, primarily serving as a key active pharmaceutical ingredient (API) in veterinary and human medicinal formulations.

Application

• Veterinary Pharmaceuticals: Primary use in the formulation of injectable, oral, and topical treatments for bacterial infections in livestock, poultry, and companion animals.
• Aquaculture: Used in medicated feeds to control bacterial diseases in fish and shrimp farming operations.
• Human Pharmaceutical Intermediates: Serves as a critical intermediate in the synthesis of advanced antibiotic derivatives and prodrugs.
• Research & Development: Utilized in microbiological research, antimicrobial susceptibility testing, and the development of new therapeutic agents.
• Feed Additives: Incorporated into specialized animal feed for disease prevention and growth promotion under regulated guidelines.
• Reference Standards: Supplied as a high-purity chemical standard for quality control and analytical testing in laboratories.

Basic Information

Product Name	Thiamphenicol
CAS No.	2393-92-2
Molecular Formula	C12H15Cl2NO5S
Molecular Weight	356.22 g/mol
Synonyms	D-Threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-(methylsulfonyl)phenethyl]acetamide; Dextrosulphenidol; Thiamphenicolum; Urfamycin; NSC-106563; Antibiotic U-17,866; Win-5063-2; (+)-Threo-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
EINECS	219-253-6

Quality Control

Our Thiamphenicol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply material compliant with various pharmacopeial monographs upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Optical Rotation	+10.5° to +12.5°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.