Description

Chloramphenicol Cinnamate is a chemically modified derivative of the broad-spectrum antibiotic chloramphenicol, where the cinnamate ester group enhances its lipophilicity and stability profile. This modification is strategically valuable for creating prodrug formulations and advanced intermediates in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel antimicrobial agents and the study of drug delivery mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel antibiotic prodrugs and derivatives.
• Antimicrobial Research: Used as a reference standard or active component in microbiological and biochemical studies targeting resistant bacterial strains.
• Prodrug Development: Exploited for its ester linkage in designing lipophilic prodrugs to improve the bioavailability and pharmacokinetic properties of parent compounds.
• Chemical Synthesis: Acts as a specialized reagent or protected intermediate in complex organic synthesis routes within fine chemical production.
• Veterinary Medicine Research: Investigated for potential applications in developing treatments for bacterial infections in animals.

Basic Information

Product Name	Chloramphenicol Cinnamate
CAS No.	14399-14-5
Molecular Formula	C24H21Cl2N2O6
Molecular Weight	504.34 g/mol
Synonyms	Chloramphenicol Cinnamic Acid Ester; D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide Cinnamate; Chloramphenicol 3-Cinnamate; Cinnamic Acid Chloramphenicol Ester; Antibiotic 3-Cinnamoylchloramphenicol; Chloromycetin Cinnamate; (1R,2R)-2-[(2,2-Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl (E)-3-phenylacrylate
EINECS	Contact for details

Quality Control

Our Chloramphenicol Cinnamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.