Description

Chloramphenicol Palmitate is a lipid-soluble ester prodrug of the broad-spectrum antibiotic chloramphenicol. This formulation is critical for enhancing the drug's palatability and bioavailability, particularly in oral pediatric suspensions. It is primarily utilized by pharmaceutical manufacturers in the production of finished dosage forms, serving as a key active pharmaceutical ingredient (API) or intermediate for global antibiotic supply chains.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic formulations, especially pediatric suspensions and syrups.
• Veterinary Medicine: Manufacture of antibiotic treatments for bacterial infections in livestock and companion animals.
• Research & Development: Used as a reference standard and biochemical tool in microbiological and pharmacological research.
• Generic Drug Production: Sourcing for manufacturers producing cost-effective generic antibiotic medications.
• Intermediate Synthesis: Serves as a precursor in the synthesis of other specialized chloramphenicol derivatives.

Basic Information

Product Name	Chloramphenicol Palmitate
CAS No.	106322-62-7
Molecular Formula	C27H42Cl2N2O6
Molecular Weight	561.54 g/mol
Synonyms	Chloramphenicol Palmitate Ester; Chloramphenicol Palmitic Acid Ester; D-(-)-Three-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide α-Palmitate; Chloramphenicol Palmitate (USP); Chloromycetin Palmitate; Levomicetina Palmitato; Cloranfenicol Palmitato
EINECS	Contact for details

Quality Control

Our Chloramphenicol Palmitate is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Each batch undergoes comprehensive analytical testing for identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and microbiological quality is provided to ensure full traceability and compliance with cGMP guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed after each use.

Specification

Item	Specification
Appearance	White to yellowish-white, fine crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbial Limits	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.