Description

Chloramphenicol Hemisuccinate is a water-soluble prodrug ester of the broad-spectrum antibiotic chloramphenicol. This chemical modification enhances its solubility for parenteral formulations, making it a critical intermediate in pharmaceutical manufacturing. It is primarily utilized by pharmaceutical companies and research institutions for the development and production of injectable antibiotic solutions.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of injectable chloramphenicol sodium succinate.
• Veterinary Medicine: Used in the formulation of treatments for bacterial infections in animals.
• Research & Development: Serves as a reference standard and active compound in microbiological and pharmacological studies.
• API (Active Pharmaceutical Ingredient) Manufacturing: An essential component in the production chain for antibiotic APIs.
• Laboratory Reagent: Used in analytical chemistry and quality control laboratories as a testing standard.

Basic Information

Product Name	Chloramphenicol Hemisuccinate
CAS No.	3544-94-3
Molecular Formula	C15H16Cl2N2O8
Molecular Weight	423.20 g/mol
Synonyms	Chloramphenicol 3'-Monosuccinate; Chloramphenicol Succinate (Ester); Chloramphenicol 21-Hemisuccinate; 2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide 3'-hydrogen succinate; NSC 406130; Antibiotic 3544-94-3; Chloramphenicol Hemisuccinate Ester
EINECS	222-593-6

Quality Control

Our Chloramphenicol Hemisuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.