Description

Z-Gly-Nh2 CAS NO 949-90-6 is a protected amino acid derivative, specifically the benzyloxycarbonyl (Z or Cbz) protected form of glycine amide. This compound serves as a crucial building block in peptide synthesis, where it provides a protected amine group that can be selectively deprotected under mild conditions. It is primarily needed by pharmaceutical researchers, peptide chemists, and manufacturers in the life sciences sector for the development of novel therapeutic agents and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for introducing a protected glycine residue into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the classical stepwise construction of peptides and peptidomimetics.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Employed to modify proteins, antibodies, or other biomolecules by introducing functional handles.
• Organic Synthesis Building Block: Utilized in the preparation of more complex organic molecules requiring a protected amino functionality.
• Research & Development: Essential for academic and industrial R&D focused on medicinal chemistry and biochemistry.

Basic Information

Product Name	Z-Gly-Nh2 CAS NO 949-90-6
CAS No.	949-90-6
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	N-Carbobenzoxyglycinamide; Cbz-Glycinamide; Z-Glycinamide; Benzyloxycarbonylglycinamide; Nα-Carbobenzyloxyglycinamide; N-(Benzyloxycarbonyl)glycinamide; Glycinamide, N-[(phenylmethoxy)carbonyl]-; NSC 3349
EINECS	213-447-5

Quality Control

Our Z-Gly-Nh2 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.