Description

4-Nitrophenylacetylene is a versatile aromatic acetylene derivative characterized by a nitro-substituted phenyl ring. This compound is a crucial high-purity building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those requiring acetylene-linked aromatic systems for biological activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, conductive materials, and liquid crystals.
• Organic Synthesis Building Block: Employed in Sonogashira coupling and other palladium-catalyzed reactions to create complex alkynes for academic and industrial research.
• Chemical Probe Development: Utilized in medicinal chemistry for creating molecular probes and imaging agents due to its reactive acetylene group.

Basic Information

Product Name	4-Nitrophenylacetylene
CAS No.	937-31-5
Molecular Formula	C8H5NO2
Molecular Weight	147.13 g/mol
Synonyms	1-Ethynyl-4-nitrobenzene; p-Nitrophenylacetylene; 4-Nitrophenylethyne; 4-Ethynylnitrobenzene; (4-Nitrophenyl)acetylene; NSC 406908; Nitrophenylacetylene
EINECS	213-333-6

Quality Control

Our 4-Nitrophenylacetylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	85 - 90 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.