Description

Cyclohexylacetylene CAS NO 931-48-6 is a versatile alkyne derivative featuring a cyclohexyl group attached to a terminal acetylene moiety. This compound is a valuable high-purity building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in creating sterically hindered alkyne linkages for targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclohexylacetylene unit contributes to specific biological activity and stability.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis & Catalysis: An essential reagent in Sonogashira coupling, click chemistry (CuAAC), and other metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for asymmetric catalysis and organometallic complexes.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value fine chemicals.

Basic Information

Product Name	Cyclohexylacetylene
CAS No.	931-48-6
Molecular Formula	C8H12
Molecular Weight	108.18 g/mol
Synonyms	Cyclohexylethyne; Ethynylcyclohexane; 1-Ethynylcyclohexane; Cyclohexyl acetylene; (Cyclohexylethynyl)benzene (related); Cyclohexane, ethynyl-; NSC 74149
EINECS	213-235-4

Quality Control

Our Cyclohexylacetylene is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable and consistent performance for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (nitrogen or argon) at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The container must be kept tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.