Description

5-Hexyn-1-ol is a versatile terminal alkyne alcohol, serving as a valuable bifunctional building block in organic synthesis. Its structure, featuring both a hydroxyl group and a terminal alkyne, makes it a critical intermediate for constructing more complex molecules via click chemistry and other coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, polymer modification, and ligand synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly through Huisgen cycloaddition (click chemistry) to create triazole linkages.
• Agrochemical Synthesis: Serves as a key precursor for creating novel herbicides, fungicides, and plant growth regulators with tailored properties.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, dendrimers, and functionalized surfaces with alkyne handles for further modification.
• Ligand & Catalyst Development: Utilized in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Employed in Sonogashira coupling, hydroalkynylation, and other C-C bond-forming reactions to elongate carbon chains or introduce acetylene functionality.
• Life Sciences & Bioconjugation: Functions as a linker molecule for attaching fluorescent dyes, peptides, or other probes to biomolecules in diagnostic and research applications.

Basic Information

Product Name	5-Hexyn-1-ol
CAS No.	928-90-5
Molecular Formula	C₆H₁₀O
Molecular Weight	98.14 g/mol
Synonyms	5-Hexyn-1-ol; 5-Hexynol; 1-Hexyn-6-ol; 6-Hydroxy-1-hexyne; Hex-5-yn-1-ol; 5-Hexyne-1-ol; 1-Hydroxy-5-hexyne; 5-Hexynyl alcohol
EINECS	213-184-5

Quality Control

Our 5-Hexyn-1-ol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.