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5-Amino-2-(3-Carboxypropanoylamino)Pentanoic Acid CAS NO 899816-95-6


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CAS No.:899816-95-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Amino-2-(3-Carboxypropanoylamino)Pentanoic Acid is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel bioactive molecules, including peptide mimetics and enzyme inhibitors. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating innovative therapeutic agents and complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly protease inhibitors and receptor antagonists.
  • Peptidomimetic Research: Used to construct modified peptide backbones that mimic natural peptides but with enhanced metabolic stability and bioavailability.
  • Bioconjugation & Linker Chemistry: The carboxylic acid and amino functionalities enable its use as a versatile linker for attaching payloads in antibody-drug conjugates (ADCs) or other bioconjugates.
  • Chemical Biology Probes: Serves as a scaffold for developing activity-based probes and inhibitors to study enzyme function and mechanism.
  • Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
  • Academic & Industrial R&D: Fundamental research into new synthetic methodologies and the exploration of structure-activity relationships (SAR).

Basic Information

Product Name 5-Amino-2-(3-Carboxypropanoylamino)Pentanoic Acid
CAS No. 899816-95-6
Molecular Formula C9H16N2O5
Molecular Weight 232.23 g/mol
Synonyms N2-(3-Carboxypropionyl)-L-ornithine; L-Ornithine, N2-(3-carboxy-1-oxopropyl)-; (S)-2-((3-Carboxypropanoyl)amino)-5-aminopentanoic acid; 5-Amino-2-(3-carboxypropanoylamino)pentanoic acid; Nα-(3-Carboxypropionyl)-L-ornithine; Succinyl-L-ornithine; N-Succinyl-L-ornithine
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Quality Control

Our 5-Amino-2-(3-Carboxypropanoylamino)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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