Description

n-Methoxy-n-Methyl 5-Thiazolecarboxamide is a high-value chemical building block, specifically a Weinreb amide derivative of a thiazole carboxylic acid. This compound is essential for the controlled synthesis of ketones and aldehydes in complex organic transformations, offering superior reactivity and selectivity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the thiazole heterocycle, which is prevalent in drugs with antimicrobial, anti-inflammatory, or anticancer properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the thiazole moiety can contribute to biological activity.
• Organic Synthesis Reagent: Serves as a versatile Weinreb amide for nucleophilic addition reactions, enabling the efficient and high-yield preparation of ketones from organometallic reagents like Grignard or organolithium compounds.
• Material Science Research: Employed as a building block for creating novel heterocyclic compounds with potential applications in organic electronics or as ligands in catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in complex, multi-step organic molecules.

Basic Information

Product Name	n-Methoxy-n-Methyl 5-Thiazolecarboxamide
CAS No.	898825-89-3
Molecular Formula	C7H10N2O2S
Molecular Weight	186.23 g/mol
Synonyms	5-Thiazolecarboxamide, N-methoxy-N-methyl-; N-Methoxy-N-methyl-5-thiazolecarboxamide; N-Methoxy-N-methylthiazole-5-carboxamide; 5-(N-Methoxy-N-methylcarbamoyl)thiazole; Thiazole-5-carboxylic acid N-methoxy-N-methylamide; Weinreb amide of 5-thiazolecarboxylic acid; 898825-89-3
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl 5-Thiazolecarboxamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.