Description

Ethyl 4-(3,5-Ditrifluoromethylphenyl)-4-Oxobutyrate is a high-value fluorinated organic intermediate characterized by its ketone and ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethylphenyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Material Science Research: Serves as a monomer or building block for creating novel fluorinated polymers and liquid crystals with unique thermal and chemical resistance properties.
• Organic Synthesis Building Block: Utilized in various name reactions, such as Michael additions or reductions, to construct more complex molecular architectures in medicinal chemistry.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 4-(3,5-Ditrifluoromethylphenyl)-4-Oxobutyrate
CAS No.	898792-91-1
Molecular Formula	C15H14F6O3
Molecular Weight	356.26 g/mol
Synonyms	Ethyl 4-Oxo-4-[3,5-bis(trifluoromethyl)phenyl]butanoate; 4-[3,5-Bis(trifluoromethyl)phenyl]-4-oxobutanoic Acid Ethyl Ester; Ethyl 4-(3,5-Bis(trifluoromethyl)benzoyl)acetate; Butanoic acid, 4-oxo-4-[3,5-bis(trifluoromethyl)phenyl]-, ethyl ester; 898792-91-1; Ethyl 3,5-bis(trifluoromethyl)benzoylacetate; Ethyl (3,5-bis(trifluoromethyl)benzoyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3,5-Ditrifluoromethylphenyl)-4-Oxobutyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.