Description

2-(3-Cyanophenyl)-2'-Iodoacetophenone is a specialized aromatic ketone building block featuring both cyano and iodo functional groups, making it a versatile intermediate for advanced synthetic chemistry. This compound is valued for its ability to undergo diverse cross-coupling and functional group transformation reactions, enabling the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in constructing biaryl and heterocyclic scaffolds common in modern therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive halogen for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodo substituent.
• Ligand and Catalyst Development: Useful for creating novel phosphine or nitrogen-based ligands for asymmetric catalysis.
• Academic & Industrial R&D: A valuable tool for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-(3-Cyanophenyl)-2'-Iodoacetophenone
CAS No.	898784-35-5
Molecular Formula	C15H10INO
Molecular Weight	347.15 g/mol
Synonyms	2'-Iodo-2-(3-cyanophenyl)acetophenone; 1-(2-Iodophenyl)-2-(3-cyanophenyl)ethan-1-one; 2-(3-Cyanophenyl)-1-(2-iodophenyl)ethanone; α-(3-Cyanophenyl)-2-iodoacetophenone; 2-Iodo-2'-(3-cyanophenyl)acetophenone; (3-Cyanophenyl)(2-iodophenyl)methanone, methylene derivative; Ethanone, 1-(2-iodophenyl)-2-(3-cyanophenyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality control includes identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results for each batch is available upon request, providing full traceability and supporting your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.