Description

8-(3-Iodophenyl)-8-Oxooctanenitrile is a high-purity, iodinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures through its reactive carbonyl and nitrile functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the iodine atom for structure-activity relationship (SAR) studies.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki and Sonogashira couplings.

Basic Information

Item	Detail
Product Name	8-(3-Iodophenyl)-8-Oxooctanenitrile
CAS No.	898767-99-2
Molecular Formula	C₁₄H₁₆INO
Molecular Weight	341.19 g/mol
Synonyms	8-Oxo-8-(3-iodophenyl)octanenitrile; 3'-Iodobenzoylcapronitrile; 8-(3-Iodobenzoyl)octanenitrile; ω-Cyano-3-iodobenzoylheptane; 3-Iodophenyl 6-cyanohexyl ketone; 6-Cyanohexyl 3-iodophenyl ketone; 1-(3-Iodophenyl)-7-cyano-1-heptanone
EINECS	Contact for details

Quality Control

Our 8-(3-Iodophenyl)-8-Oxooctanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.