Description

8-(4-Iodophenyl)-8-Oxooctanenitrile is a specialized organic intermediate featuring a phenyl ring substituted with an iodine atom and a nitrile-terminated aliphatic keto chain. This unique bifunctional structure makes it a valuable building block for the synthesis of more complex molecules in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and functional material design.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or as enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators, leveraging the reactivity of both the aryl iodide and ketone functional groups.
• Liquid Crystal & OLED Material Synthesis: Acts as a building block for creating advanced organic electronic materials due to its rigid aromatic core and modifiable side chain.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to construct complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, where the iodine can serve as a handle for further modification or labeling.
• Polymer & Resin Modification: The nitrile and ketone groups can be incorporated into polymer backbones or used to modify resin properties for specialized coatings or adhesives.

Basic Information

Product Name	8-(4-Iodophenyl)-8-Oxooctanenitrile
CAS No.	898767-90-3
Molecular Formula	C₁₄H₁₆INO
Molecular Weight	341.19 g/mol
Synonyms	8-Oxo-8-(4-iodophenyl)octanenitrile; 4'-Iodobenzoylcapronitrile; 8-(4-Iodobenzoyl)octanenitrile; ω-Cyano-4-iodobenzoylpentane; 1-(4-Iodophenyl)-1,7-dioxoheptanenitrile; 4-Iodophenyl 6-cyanohexyl ketone; 6-Cyanohexyl 4-iodophenyl ketone; 8-(p-Iodophenyl)-8-oxooctanenitrile
EINECS	Contact for details

Quality Control

Our 8-(4-Iodophenyl)-8-Oxooctanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.