Description

8-(2-Fluorophenyl)-8-Oxooctanoic Acid is a high-purity fluorinated aromatic keto acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides where the fluorophenyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated monomers for advanced polymers with unique thermal and chemical resistance properties.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	8-(2-Fluorophenyl)-8-Oxooctanoic Acid
CAS No.	898766-58-0
Molecular Formula	C₁₄H₁₇FO₃
Molecular Weight	252.28 g/mol
Synonyms	8-Oxo-8-(2-fluorophenyl)octanoic Acid; 2-Fluoro-ω-oxobenzeneoctanoic Acid; 8-(2-Fluorobenzoyl)octanoic Acid; ω-Oxo-2-fluorophenyloctanoic Acid; FPOA; 2-Fluorophenyl 7-carboxyheptyl ketone; Octanoic acid, 8-(2-fluorophenyl)-8-oxo-
EINECS	Contact for details

Quality Control

Every batch of 8-(2-Fluorophenyl)-8-Oxooctanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.