Description

8-(2,5-Difluorophenyl)-8-Oxooctanoic Acid is a high-purity, specialized organic building block featuring a difluorophenyl ketone moiety linked to a medium-chain carboxylic acid. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators leveraging the difluorophenyl group for enhanced bioactivity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic semiconductors.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new chemical spaces in organic synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	8-(2,5-Difluorophenyl)-8-Oxooctanoic Acid
CAS No.	898766-40-0
Molecular Formula	C₁₄H₁₆F₂O₃
Molecular Weight	270.27 g/mol
Synonyms	8-Oxo-8-(2,5-difluorophenyl)octanoic acid; 2,5-Difluoro-ω-oxobenzeneoctanoic acid; Octanoic acid, 8-(2,5-difluorophenyl)-8-oxo-; 898766-40-0; 8-(2,5-Difluorobenzoyl)octanoic acid; ω-Oxo-2,5-difluorobenzeneoctanoic acid
EINECS	Contact for details

Quality Control

Our 8-(2,5-Difluorophenyl)-8-Oxooctanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.