Description

5-(3-Fluoro-4-Methylphenyl)-5-Oxovaleric Acid is a high-purity, versatile organic intermediate featuring a fluorinated aromatic ketone moiety linked to a valeric acid chain. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom and aromatic ketone group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers or advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Used in exploratory chemistry within university laboratories and corporate R&D centers for novel compound library generation.

Basic Information

Product Name	5-(3-Fluoro-4-Methylphenyl)-5-Oxovaleric Acid
CAS No.	898765-93-0
Molecular Formula	C12H13FO3
Molecular Weight	224.23 g/mol
Synonyms	5-Oxo-5-(3-fluoro-4-methylphenyl)pentanoic acid; 4-(3-Fluoro-4-methylbenzoyl)butyric acid; 3-Fluoro-4-methyl-γ-oxobenzenebutanoic acid; 5-(3-Fluoro-p-tolyl)-5-oxopentanoic acid; δ-Oxo-δ-(3-fluoro-4-methylphenyl)valeric acid; 898765-93-0; 5-(3-Fluoro-4-methylphenyl)-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(3-Fluoro-4-Methylphenyl)-5-Oxovaleric Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.