Description

Ethyl 2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyrate is a high-purity fluorinated organic ester compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacologically active molecules. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory pathways, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Employed as a monomer or precursor for developing specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology Probes: Serves as a starting material for creating fluorinated probes and tags used in biochemical assays and diagnostic research.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of fluorinated fine chemicals.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Ethyl 2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyrate
CAS No.	898753-65-6
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	Ethyl 4-(3-Fluorobenzoyl)-2,2-dimethylbutyrate; 4-(3-Fluorophenyl)-4-oxo-2,2-dimethylbutanoic Acid Ethyl Ester; 3-Fluorophenyl 2,2-Dimethyl-4-oxobutanoate Ethyl Ester; Butanoic acid, 4-(3-fluorophenyl)-4-oxo-2,2-dimethyl-, ethyl ester; Ethyl 2,2-dimethyl-4-oxo-4-(3-fluorophenyl)butanoate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.