Description

Ethyl 8-(2-Fluorophenyl)-8-Oxooctanoate is a high-purity fluorinated ketoester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a flexible aliphatic chain terminated with an ester, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that leverage the fluorine atom for enhanced bioactivity and stability.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and liquid crystals, where the fluorine group can impart unique surface properties.
• Chemical Synthesis Reagent: Employed in organic reactions such as Friedel-Crafts acylation, reduction, or hydrolysis to generate more complex fluorinated derivatives.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).

Basic Information

Product Name	Ethyl 8-(2-Fluorophenyl)-8-Oxooctanoate
CAS No.	898753-44-1
Molecular Formula	C₁₆H₂₁FO₃
Molecular Weight	280.34 g/mol
Synonyms	Ethyl 8-oxo-8-(2-fluorophenyl)octanoate; 8-(2-Fluorophenyl)-8-oxooctanoic Acid Ethyl Ester; 2-Fluorophenyl 7-Carbethoxyheptyl Ketone; Octanoic acid, 8-(2-fluorophenyl)-8-oxo-, ethyl ester; Ethyl 8-(o-Fluorophenyl)-8-oxooctanoate; FPOE; Ketoester 898753-44-1
EINECS	Contact for details

Quality Control

Our Ethyl 8-(2-Fluorophenyl)-8-Oxooctanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.