Description

Ethyl 5-(3-Fluorophenyl)-5-Oxovalerate is a high-purity fluorinated keto ester building block, essential for advanced organic synthesis and pharmaceutical research. Its molecular structure, featuring a fluorophenyl ketone moiety, makes it a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic ring, which can influence potency, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Serves as a precursor for developing new fluorinated pesticides and herbicides, where the fluorine atom enhances lipophilicity and environmental stability.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Ethyl 5-(3-Fluorophenyl)-5-Oxovalerate
CAS No.	898752-10-8
Molecular Formula	C13H15FO3
Molecular Weight	238.26 g/mol
Synonyms	Ethyl 5-(3-Fluorobenzoyl)valerate; 5-(3-Fluorobenzoyl)pentanoic Acid Ethyl Ester; Ethyl 5-(3-Fluorobenzoyl)pentanoate; 3-Fluorophenyl 5-ethoxy-5-oxopentyl ketone; 5-Oxo-5-(3-fluorophenyl)pentanoic Acid Ethyl Ester; Ethyl 5-Oxo-5-(m-fluorophenyl)valerate; Ethyl δ-Oxo-δ-(3-fluorophenyl)valerate; m-Fluorobenzoylbutyric Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(3-Fluorophenyl)-5-Oxovalerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.