Description

4-Chloro-n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-3-Nitrobenzamide is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. Its intricate molecular structure, featuring a benzamide core with fluorophenyl, nitro, and sulfone functional groups, makes it a valuable building block for synthesizing novel bioactive compounds. This product is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents or crop protection solutions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small-molecule entities.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Employed in the research phase for creating novel active ingredients for crop protection products, leveraging its heterocyclic and halogenated structure.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological pathways and protein functions within academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized intermediate.

Basic Information

Product Name	4-Chloro-n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-3-Nitrobenzamide
CAS No.	898619-59-5
Molecular Formula	C22H18ClFN2O6S
Molecular Weight	492.90 g/mol
Synonyms	4-Chloro-N-(1,1-dioxido-1,2-thiolan-3-yl)-N-[[5-(4-fluorophenyl)-2-furyl]methyl]-3-nitrobenzamide; 4-Chloro-N-(1,1-dioxotetrahydro-3-thienyl)-N-{[5-(4-fluorophenyl)-2-furyl]methyl}-3-nitrobenzamide; Benzamide, 4-chloro-N-(1,1-dioxido-1,2-thiolan-3-yl)-N-[[5-(4-fluorophenyl)-2-furyl]methyl]-3-nitro-; 898619-59-5; 4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-({5-(4-fluorophenyl)furan-2-yl}methyl)-3-nitrobenzamide
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-3-Nitrobenzamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) as indicated by its chemical properties. Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.