Description

(2-Amino-4-Chlorophenyl)(Pyrrolidin-1-Yl)Methanone is a high-purity, functionalized aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both an amino-chlorophenyl moiety and a pyrrolidine amide, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the pyrrolidine scaffold.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the chlorophenyl group can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, dyes, or photoactive materials for electronic applications.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology development in university and CRO laboratories.
• Custom Synthesis Building Block: Provides a handle for further functionalization, enabling the rapid generation of compound libraries for high-throughput screening.

Basic Information

Product Name	(2-Amino-4-Chlorophenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	898541-51-0
Molecular Formula	C11H13ClN2O
Molecular Weight	224.69 g/mol
Synonyms	1-(2-Amino-4-chlorophenyl)-2-pyrrolidin-1-ylethanone; 2-Amino-4-chloro-N-(pyrrolidin-1-yl)benzamide; 2-Amino-4-chlorobenzoylpyrrolidine; 898541-51-0; (2-Amino-4-chlorophenyl)(pyrrolidin-1-yl)methanone; Pyrrolidine, 1-[(2-amino-4-chlorobenzoyl)]-; N-(2-Amino-4-chlorobenzoyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (2-Amino-4-Chlorophenyl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.