Description

4-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid is a high-purity, functionalized benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with specific piperazine and carbonyl functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients. Its precise structure allows for targeted modifications in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore new chemical entities by modifying the piperazine-acetyl and benzoic acid moieties.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators requiring specific heterocyclic amide structures.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or affinity probes used in biochemical and cellular target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	4-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid
CAS No.	896508-20-6
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	4-[(4-Acetyl-1-piperazinyl)carbonyl]benzoic acid; 4-(4-Acetylpiperazine-1-carbonyl)benzoic Acid; Benzoic acid, 4-[(4-acetyl-1-piperazinyl)carbonyl]-; 4-Carboxy-N-(4-acetylpiperazin-1-yl)benzamide; Terephthalic acid mono-(4-acetyl-piperazin-1-ylamide); 896508-20-6; 4-(4-Acetylpiperazine-1-carbonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-[(4-Acetylpiperazin-1-Yl)Carbonyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and process development standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.