Description

n-(2-Bromo-4,6-Difluorophenyl)-2,2-Diphenylethanamide is a specialized brominated and fluorinated aromatic amide compound, serving as a crucial high-purity building block in advanced organic synthesis. Its molecular architecture, featuring halogen substituents and a diphenylacetyl moiety, makes it an invaluable intermediate for constructing complex molecules with targeted properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, where the halogenated aromatic system can contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials requiring halogenated aromatic units.
• Chemical Biology Probe Synthesis: Employed in creating labeled compounds or molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Essential for fine chemical and custom synthesis houses producing tailored intermediates for client-specific R&D and scale-up projects.

Basic Information

Product Name	n-(2-Bromo-4,6-Difluorophenyl)-2,2-Diphenylethanamide
CAS No.	895370-02-2
Molecular Formula	C20H14BrF2NO
Molecular Weight	402.24 g/mol
Synonyms	2-Bromo-4,6-difluoro-N-(2,2-diphenylacetyl)aniline; 2,2-Diphenyl-N-(2-bromo-4,6-difluorophenyl)acetamide; N-(2-Bromo-4,6-difluorophenyl)-2,2-diphenylacetamide; 895370-02-2; 2-Bromo-4,6-difluoro-N-(diphenylacetyl)aniline; Diphenylacetic acid (2-bromo-4,6-difluoroanilide); (2-Bromo-4,6-difluorophenyl)(2,2-diphenylacet)amide
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-4,6-Difluorophenyl)-2,2-Diphenylethanamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥97% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity (IR, NMR), purity (HPLC), and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material tailored to meet specific customer specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.