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(R)-(+)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine, Min. 97% CAS NO 894771-25-6


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CAS No.:894771-25-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(+)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine, Min. 97% is a high-purity, chiral ferrocenyl phosphine ligand, a critical component in asymmetric catalysis. This compound matters because it enables highly enantioselective transformations, allowing for the efficient and cost-effective synthesis of single-enantiomer intermediates essential for advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes and scaling up production of chiral active ingredients.

Application

  • Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
  • Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in the manufacture of active pharmaceutical ingredients (APIs), including cardiovascular, CNS, and antiviral drugs.
  • Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, and fragrances with high optical purity.
  • Cross-Coupling Reactions: Can serve as a supporting ligand in palladium-catalyzed cross-coupling reactions to form C-C and C-X bonds.
  • Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic cycles in asymmetric synthesis.

Basic Information

Product Name (R)-(+)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine, Min. 97%
CAS No. 894771-25-6
Molecular Formula C51H46FeP2
Molecular Weight 768.69 g/mol
Synonyms (R,R)-JOSIPHOS SL-J009-1; (R)-(+)-1-[(S)-2-(2-Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine; Josiphos SL-J009-1; (R)-1-[(S)-2-(2-Diphenylphosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; (R)-1-[(S)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldi(3,5-xylyl)phosphine; JOSIPHOS ligand SL-J009-1; Ferrocenyl phosphine ligand SL-J009-1
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Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management to ensure consistent high performance in sensitive catalytic applications. We guarantee a minimum purity of 97%, with typical purity often exceeding this specification. Identity and purity are confirmed by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profile is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized and moisture-sensitive; the container should be allowed to reach room temperature before opening to prevent condensation. Store away from strong oxidizing agents.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) Min. 97.0%
Chiral Purity (HPLC) Min. 99.0% ee
Loss on Drying Max. 0.5%
Residue on Ignition Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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