Description

1-(4-Methylphenyl)Piperazin-2-One is a high-purity, specialized heterocyclic compound featuring a piperazinone core substituted with a p-tolyl group. This structural motif makes it a valuable and versatile pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical synthesis specialists seeking to build complex molecular architectures for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, such as antipsychotics or antidepressants.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) and create novel chemical libraries.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, where the piperazinone ring is a critical pharmacophore.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-(4-Methylphenyl)Piperazin-2-One
CAS No.	893748-24-8
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	1-(p-Tolyl)piperazin-2-one; 1-(4-Methylphenyl)-2-piperazinone; 2-Piperazinone, 1-(4-methylphenyl)-; 4-Methyl-N-(2-oxopiperazin-1-yl)aniline; 1-(4-Methylphenyl)-1,4-diazepan-2-one; 893748-24-8; p-Tolylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.