Description

[2,2-Dimethyl-1-(2-Oxo-Ethyl)-Propyl]-Carbamic Acid tert-Butyl Ester is a specialized, high-purity chemical intermediate featuring a protected amine and a reactive ketone functional group. This compound is critical for enabling complex multi-step syntheses in advanced pharmaceutical research and development, offering precise control over molecular architecture. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring the introduction of a protected amino ketone moiety.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation therapies.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Ligand & Catalyst Development: Employed in organic and organometallic chemistry for creating novel chiral ligands and catalysts.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	[2,2-Dimethyl-1-(2-Oxo-Ethyl)-Propyl]-Carbamic Acid tert-Butyl Ester
CAS No.	892874-26-9
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	tert-Butyl N-[2,2-dimethyl-3-oxobutyl]carbamate; 3-Oxo-2,2-dimethylbutylcarbamic Acid tert-Butyl Ester; 1-Boc-amino-3,3-dimethyl-4-butanone; 3,3-Dimethyl-4-oxo-butyl-carbamic Acid tert-Butyl Ester; N-Boc-3-amino-3-methylbutanone; (3-Oxo-2,2-dimethyl-butyl)-carbamic Acid tert-Butyl Ester; Boc-Aminopivaldehyde Acetone Adduct; 1-(tert-Butoxycarbonylamino)-3,3-dimethylbutan-2-one
EINECS	Contact for details

Quality Control

Every batch of [2,2-Dimethyl-1-(2-Oxo-Ethyl)-Propyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for advanced synthetic applications. Our products are supported by comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to ensure supply chain integrity and batch-to-batch consistency for our global pharmaceutical and research clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.