Description

3-(2-Chlorophenyl)-n-[4-(4-Methylphenyl)-1,2,5-Oxadiazol-3-Yl]Acrylamide is a specialized organic compound belonging to the class of acrylamide derivatives containing a 1,2,5-oxadiazole (furazan) heterocycle. This compound matters as a high-value chemical building block and pharmacological research intermediate, particularly in the development of novel small molecule therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and synthesis of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the research and development of new drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions in academic and industrial research settings.
• Material Science Research: Potential monomer or additive in the development of advanced polymers with specific optical or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Product Name	3-(2-Chlorophenyl)-n-[4-(4-Methylphenyl)-1,2,5-Oxadiazol-3-Yl]Acrylamide
CAS No.	892636-47-4
Molecular Formula	C18H14ClN3O2
Molecular Weight	339.78 g/mol
Synonyms	N-[4-(4-Methylphenyl)-1,2,5-oxadiazol-3-yl]-3-(2-chlorophenyl)acrylamide; 3-(2-Chlorophenyl)-N-[4-(p-tolyl)-1,2,5-oxadiazol-3-yl]prop-2-enamide; 3-(2-Chlorophenyl)-N-(4-(4-methylphenyl)-1,2,5-oxadiazol-3-yl)acrylamide; 892636-47-4; Acrylamide, 3-(2-chlorophenyl)-N-[4-(4-methylphenyl)-1,2,5-oxadiazol-3-yl]-; Furazan acrylamide derivative; p-Tolylfurazan acrylamide chlorophenyl derivative
EINECS	Contact for details

Quality Control

Our 3-(2-Chlorophenyl)-n-[4-(4-Methylphenyl)-1,2,5-Oxadiazol-3-Yl]Acrylamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.5% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.