Description

Etaracizumab CAS NO 892553-42-3 is a high-purity, monoclonal antibody-based compound designed for advanced research and development applications. This product is critical for scientists and pharmaceutical developers working on targeted therapeutic interventions. It is primarily utilized in the biotechnology and pharmaceutical industries for preclinical studies, mechanism of action research, and as a key reference standard.

Application

• Biopharmaceutical Research: Used as a reference standard and active ingredient in the development of novel biologic drugs and targeted therapies.
• Preclinical Studies: Essential for in vitro and in vivo studies to investigate efficacy, pharmacokinetics, and pharmacodynamics.
• Mechanism of Action (MoA) Analysis: Employed to study specific biological pathways and target validation in disease models.
• Assay Development: Serves as a critical component in the development and validation of diagnostic and analytical assays (e.g., ELISA, cell-based assays).
• Process Development & Scale-up: Used in upstream and downstream process optimization for biomanufacturing.
• Quality Control & Stability Testing: Acts as a benchmark for purity, potency, and stability testing of biologic products.

Basic Information

Product Name	Etaracizumab
CAS No.	892553-42-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Etaracizumab; Anti-αvβ3 Integrin Monoclonal Antibody; Abegrin; MEDI-522; Monoclonal Antibody MEDI-522; Humanized Monoclonal Antibody against Integrin αvβ3; Vitaxin II
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, potency, and biological activity. Certificates of Analysis (COA) detailing specifications such as purity by SEC-HPLC, endotoxin levels, and biological assay results are available upon request. We adhere to stringent quality management systems suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot as necessary to maintain product integrity.

Specification

Item	Specification
Appearance	Clear to slightly opalescent, colorless to pale yellow solution
Identification (SEC-HPLC / MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Concentration	As per COA (typically 1-10 mg/mL)
Endotoxin	< 1.0 EU/mg
Biological Activity (Cell-based Assay)	As per COA
Buffer	Typically in PBS, pH 7.2-7.4

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.