Description

n-(2-Boc-Amino-Ethyl)-Succinamic Acid CAS NO 891781-87-6 is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis and pharmaceutical research. This compound is essential for the controlled synthesis of peptides and complex molecules, offering precise control over molecular architecture. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in drug discovery and the production of advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected glutamic acid or aspartic acid analog for introducing specific side-chain functionalities.
• Linker Chemistry: Serves as a versatile bifunctional linker in bioconjugation and the development of antibody-drug conjugates (ADCs) and prodrugs.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines, crucial in multi-step synthetic routes.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other bioactive compounds for research purposes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	n-(2-Boc-Amino-Ethyl)-Succinamic Acid
CAS No.	891781-87-6
Molecular Formula	C11H20N2O5
Molecular Weight	260.29 g/mol
Synonyms	N-(2-((tert-Butoxycarbonyl)amino)ethyl)succinamic Acid; 2-[(2-{[(tert-Butoxycarbonyl)amino]ethyl}amino)-2-oxoethyl]acetic Acid; Boc-NH-CH2-CH2-NH-CO-CH2-CH2-COOH; N-(2-(Boc-amino)ethyl)succinamic Acid; Succinamic Acid, N-[2-[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; BOC-AEEA-OH; (2-{2-[(tert-Butoxycarbonyl)amino]ethylamino}-2-oxoethyl)acetic Acid
EINECS	Contact for details

Quality Control

Our n-(2-Boc-Amino-Ethyl)-Succinamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with high-purity standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.