Description

1-(3-Boc-Amino-Phenyl)-Ethanol is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in providing a versatile, protected amine handle for the controlled construction of complex pharmaceutical intermediates and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally defined synthons for API development and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phenethylamine or amino alcohol motifs.
• Peptidomimetic Synthesis: Used in the construction of non-peptide scaffolds that mimic peptide structure and function for drug discovery.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis and metal complexation.
• Agrochemical Active Ingredient Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.
• Material Science Research: Building block for novel polymers and functional organic materials requiring specific amine-alcohol functionality.
• Academic & Contract Research: Valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1-(3-Boc-Amino-Phenyl)-Ethanol
CAS No.	889956-70-1
Molecular Formula	C₁₃H₁₉NO₃
Molecular Weight	237.29 g/mol
Synonyms	1-(3-((tert-Butoxycarbonyl)amino)phenyl)ethanol; 3-(1-Hydroxyethyl)phenylcarbamic Acid tert-Butyl Ester; 1-[3-[(tert-Butoxycarbonyl)amino]phenyl]ethan-1-ol; N-Boc-3-(1-Hydroxyethyl)aniline; tert-Butyl [3-(1-hydroxyethyl)phenyl]carbamate; 1-(3-Boc-aminophenyl)ethan-1-ol; (3-(1-Hydroxyethyl)phenyl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 1-(3-Boc-Amino-Phenyl)-Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and all relevant physical-chemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.