Description

3-Chloro-5-Iodo-L-Tyrosine is a halogenated derivative of the essential amino acid L-Tyrosine, serving as a critical building block in advanced organic synthesis and pharmaceutical research. This modified amino acid is particularly valuable for its role in the development of novel radiopharmaceuticals and as a precursor for complex peptide-based compounds. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of targeted therapies and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel thyroid hormone analogs and receptor-targeting drugs.
• Radiopharmaceutical Development: Used in research for labeling with radioisotopes (e.g., I-123, I-131) for diagnostic imaging and therapeutic applications.
• Peptide Synthesis: Incorporated into specialized peptide sequences to study structure-activity relationships and create bioactive molecules.
• Biochemical Research: Serves as a tool compound in enzymatic studies, particularly those involving tyrosine kinases and halogenase enzymes.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Employed in medicinal chemistry for the construction of complex molecules with specific halogen substitutions.

Basic Information

Product Name	3-Chloro-5-Iodo-L-Tyrosine
CAS No.	889871-36-7
Molecular Formula	C9H9ClINO3
Molecular Weight	341.53 g/mol
Synonyms	L-Tyrosine, 3-chloro-5-iodo-; (2S)-2-Amino-3-(3-chloro-5-iodo-4-hydroxyphenyl)propanoic acid; 3-Cl-5-I-Tyr; 3-Chloro-5-iodotyrosine; 3-Chloro-5-iodo-L-tyrosine; 3-Chloro-5-iodo-DL-tyrosine (related); Halogenated tyrosine derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Iodo-L-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the L-configuration, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-Isomer
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.