Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[13-(4-Formylphenyl)-13-Oxo-3,6,9-Trioxa-12-Azatridec-1-Yl]Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a high-purity, complex heterocyclic compound designed for advanced research and pharmaceutical development. This molecule serves as a critical synthetic intermediate or building block for creating novel active pharmaceutical ingredients (APIs) and bioconjugates, particularly in targeted drug delivery systems. It is essential for R&D chemists and process development scientists working in oncology, diagnostics, and advanced therapeutic modalities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drugs and targeted therapeutics.
• Bioconjugation & Linker Chemistry: Used to attach cytotoxic agents, imaging probes, or other functional moieties to antibodies, proteins, or peptides for Antibody-Drug Conjugates (ADCs) and other targeted therapies.
• Proteolysis-Targeting Chimeras (PROTACs): Serves as a component in the design of heterobifunctional molecules for targeted protein degradation.
• Chemical Biology Research: Tool compound for studying enzyme inhibition, receptor binding, and cellular signaling pathways.
• Diagnostic Agent Development: Intermediate in the production of contrast agents or molecular probes for imaging (e.g., PET, MRI).
• Material Science: Potential precursor for specialized polymers or coatings with unique electronic or biological properties.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[13-(4-Formylphenyl)-13-Oxo-3,6,9-Trioxa-12-Azatridec-1-Yl]Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	889443-90-7
Molecular Formula	C28H36N4O8S
Molecular Weight	588.68 g/mol
Synonyms	Biotin-PEG4-CHO alkyne; Biotin-PEG4-Alkyne-CHO; (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl pentanamide derivative; N-[13-(4-Formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; Biotin-PEG4-alkyne benzaldehyde; Biotinylated PEG alkyne benzaldehyde linker; Biotin-PEG4-Alkyne-CHO; Biotin-PEG4-alkyne-CHO linker.
EINECS	Contact for details

Quality Control

Our production of 1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[13-(4-Formylphenyl)-13-Oxo-3,6,9-Trioxa-12-Azatridec-1-Yl]Hexahydro-2-Oxo-, (3As,4S,6Ar)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development under quality systems suitable for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability, as the compound is easily oxidized. For short-term use, store desiccated at 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by NMR)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.