Description

4-[3-(Hydroxymethyl)Phenoxy]Benzonitrile is a versatile aromatic ether nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its bifunctional structure, featuring both a hydroxymethyl and a nitrile group, makes it a valuable building block for constructing complex molecules with tailored properties. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its aromatic backbone for bioactivity.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or mesogenic unit in the production of specialty polymers and liquid crystal displays (LCDs).
• Organic Electronics: Acts as a building block for electron-transport materials and other components in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: The nitrile and hydroxymethyl groups provide handles for palladium-catalyzed and other metal-mediated coupling reactions.

Basic Information

Product Name	4-[3-(Hydroxymethyl)Phenoxy]Benzonitrile
CAS No.	888967-63-3
Molecular Formula	C14H11NO2
Molecular Weight	225.24 g/mol
Synonyms	3-[(4-Cyanophenoxy)methyl]phenol; 4-(3-Hydroxybenzyloxy)benzonitrile; Benzonitrile, 4-[3-(hydroxymethyl)phenoxy]-; 4-(3-Hydroxymethyl-phenoxy)-benzonitrile; 3-(Hydroxymethyl)phenyl 4-cyanophenyl ether; 4-Cyanophenyl 3-(hydroxymethyl)phenyl ether
EINECS	Contact for details

Quality Control

Our 4-[3-(Hydroxymethyl)Phenoxy]Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.