Description

Potassium Trifluoro[(Thien-2-Yl)Methyl]Borate is an organoboron reagent, specifically a potassium trifluoroborate salt, that serves as a stable, air- and moisture-tolerant alternative to boronic acids in cross-coupling reactions. This compound is valued for its enhanced stability and handling properties, which facilitate more reliable and scalable synthetic processes. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules, particularly in Suzuki-Miyaura couplings.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides containing thiophene-based structures.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a robust and user-friendly coupling partner with various organic halides or triflates under palladium catalysis.
• Chemical Library Development: Utilized in medicinal chemistry for the parallel synthesis of diverse compound libraries for screening.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands or metal-organic complexes.

Basic Information

Product Name	Potassium Trifluoro[(Thien-2-Yl)Methyl]Borate
CAS No.	888711-49-7
Molecular Formula	C5H5BF3KS
Molecular Weight	203.06 g/mol
Synonyms	Potassium (Thiophen-2-ylmethyl)trifluoroborate; Potassium (2-Thienylmethyl)trifluoroborate; (Thiophen-2-ylmethyl)trifluoroboronic Acid Potassium Salt; 2-Thienylmethyltrifluoroborate Potassium Salt; Potassium Trifluoro(2-thienylmethyl)borate; Potassium (Thien-2-ylmethyl)trifluoroborate; Potassium Trifluoro[(2-thienyl)methyl]borate; Potassium Trifluoro[(thiophen-2-yl)methyl]borate(1-)
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro[(Thien-2-Yl)Methyl]Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity, and KF titration for moisture content, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) with full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹¹B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0 %
Potassium Content	18.5 - 20.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.