Description

Methanesulfonamide, n-[(2,3-Dihydro-1,1-Dioxido-3-Oxo-1,2-Benzisothiazol-6-Yl)Methyl]- is a specialized organic intermediate featuring a benzisothiazole dioxido core functionalized with a methanesulfonamide group. This compound is of significant value in advanced pharmaceutical synthesis and agrochemical research due to its unique heterocyclic structure, which serves as a key building block for developing novel active ingredients. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function or protein interactions in biological systems.
• Material Science Research: Potential intermediate for synthesizing specialty polymers or organic electronic materials due to its sulfonamide and heterocyclic functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	Methanesulfonamide, n-[(2,3-Dihydro-1,1-Dioxido-3-Oxo-1,2-Benzisothiazol-6-Yl)Methyl]-
CAS No.	888225-62-5
Molecular Formula	C9H8N2O5S2
Molecular Weight	288.30 g/mol
Synonyms	6-[(Methanesulfonylamino)methyl]-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide; N-[(2,3-Dihydro-1,1-dioxido-3-oxo-1,2-benzisothiazol-6-yl)methyl]methanesulfonamide; 1,2-Benzisothiazol-3(2H)-one, 6-[(methylsulfonylamino)methyl]-, 1,1-dioxide; Saccharin derivative methanesulfonamide; 6-(Methanesulfonamidomethyl)saccharin
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, n-[(2,3-Dihydro-1,1-Dioxido-3-Oxo-1,2-Benzisothiazol-6-Yl)Methyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full batch traceability are provided to guarantee supply reliability and consistent quality for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.