Description

2-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile is a versatile and high-value pharmaceutical intermediate featuring a benzonitrile core linked to a hydroxy-substituted piperidine ring. This molecular architecture makes it a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-purity intermediates for advanced drug discovery and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways.
• API Manufacturing: Employed in the scaled-up production of specific active pharmaceutical ingredients requiring its unique piperidine-benzonitrile scaffold.

Basic Information

Product Name	2-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile
CAS No.	887593-80-8
Molecular Formula	C12H14N2O
Molecular Weight	202.26 g/mol
Synonyms	2-(4-Hydroxypiperidin-1-yl)benzonitrile; 1-(2-Cyanophenyl)-4-piperidinol; 4-Hydroxy-1-(2-cyanophenyl)piperidine; 2-(4-Hydroxy-1-piperidinyl)benzonitrile; 2-(4-Hydroxypiperidino)benzonitrile; 2-(4-Hydroxy-piperidin-1-yl)-benzonitrile; 2-(4-Hydroxy-1-piperidyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.