Description

4-Chloro-2,3-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the phenylacetic acid moiety with specific halogen substitution patterns, enabling precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluoro and chloro substituents contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new fluorination methodologies.
• Fine Chemical Production: Acts as a building block for synthesizing complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	4-Chloro-2,3-Difluorophenylacetic Acid
CAS No.	887586-54-1
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	2-(4-Chloro-2,3-difluorophenyl)acetic Acid; (4-Chloro-2,3-difluorophenyl)acetic Acid; 4-Chloro-2,3-difluorobenzeneacetic Acid; α-(4-Chloro-2,3-difluorophenyl)acetic Acid; NSC 405124; 887586-54-1; 4-Chloro-2,3-difluoro-α-toluic Acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-Difluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.