Description

1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Piperidine is a high-value, protected piperidine derivative serving as a critical building block in advanced organic synthesis. Its core value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new drug candidates, especially within the fields of central nervous system (CNS) agents, receptor modulators, and other bioactive small molecules. The Boc-protected amine and bromoaryl functionalities offer orthogonal reactivity for precise, multi-step synthetic sequences.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid surrogate in the design of peptide-like bioactive compounds.
• Ligand and Receptor Probe Development: Employed in the creation of specific ligands for studying biological targets and pathways.
• Chemical Biology Tool Development: Utilized to create molecular probes for investigating enzyme function and cellular processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects at gram to kilogram scale for clinical trial material production.

Basic Information

Product Name	1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Piperidine
CAS No.	887584-63-6
Molecular Formula	C18H27BrN2O2
Molecular Weight	383.33 g/mol
Synonyms	1-Boc-3-[2-(4-Bromophenyl)ethylamino]piperidine; tert-Butyl 3-[(2-(4-bromophenyl)ethyl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[(2-(4-bromophenyl)ethyl)amino]piperidine; 3-[(2-(4-Bromophenyl)ethyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-3-[(2-(4-bromophenyl)ethyl)amino]piperidine; Piperidine, 3-[(2-(4-bromophenyl)ethyl)amino]-, 1-(1,1-dimethylethyl) 1-carbamate
EINECS	Contact for details

Quality Control

Our 1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We can support development projects requiring material that meets internal specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.