Description

1-Bromo-4-Propyloxy-2,3-Difluorobenzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound is valued for its unique combination of bromine and fluorine substituents, which provide distinct reactivity and electronic properties for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoro and propyloxy groups contribute to bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the synthesis of fluorinated aromatic cores used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal and chemical resistance.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-Bromo-4-Propyloxy-2,3-Difluorobenzene
CAS No.	887582-69-6
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	2,3-Difluoro-4-bromophenyl propyl ether; 4-Bromo-2,3-difluorophenyl propyl ether; 1-Bromo-4-(propoxy)-2,3-difluorobenzene; Benzene, 1-bromo-4-(propoxy)-2,3-difluoro-; 2,3-Difluoro-4-bromo-1-propoxybenzene; 4-Bromo-2,3-difluoro-1-propoxybenzene; Propyl 2,3-difluoro-4-bromophenyl ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Propyloxy-2,3-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures reliable batch-to-batch consistency, which is critical for your research and process development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to the presence of fluoride, ensure the container is properly sealed and compatible with halogenated organics.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.