Description

1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Pyrrolidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Serves as a key building block for constructing complex molecular architectures of potential Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• CNS Drug Research: Particularly relevant in the research and development of ligands and modulators for central nervous system targets.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Pyrrolidine
CAS No.	887578-47-4
Molecular Formula	C17H25BrN2O2
Molecular Weight	369.30 g/mol
Synonyms	tert-Butyl 3-[2-(4-bromophenyl)ethylamino]pyrrolidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[2-(4-bromophenyl)ethylamino]pyrrolidine; 1-Boc-3-[(2-(4-bromophenyl)ethyl)amino]pyrrolidine; N-(tert-Butoxycarbonyl)-3-[2-(4-bromophenyl)ethylamino]pyrrolidine; 3-[2-(4-Bromophenyl)ethylamino]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; Pyrrolidine, 3-[2-(4-bromophenyl)ethylamino]-, 1-(1,1-dimethylethyl) ester; 887578-47-4
EINECS	Contact for details

Quality Control

Our 1-Boc-3-[2-(4-Bromo-Phenyl)-Ethylamino]-Pyrrolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While typically supplied as a research-grade chemical, production can be aligned with specific customer requirements, including higher purity grades for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.